Quantitative estimation of calcium dynamics from ratiometric
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چکیده
Quantitative estimation of calcium dynamics from ratiometric 1 measurements: a direct, non-ratioing, method 2 3 4 5 Sébastien Joucla , Andreas Pippow 2 , 6 Peter Kloppenburg 2 and Christophe Pouzat 7 8 9 10 1 Cerebral Physiology Laboratory, Université Paris-Descartes, CNRS, UMR 8118, 11 45 rue des Saints-Pères, 75006 Paris, France 12 13 14 2 Institute of Zoology and Physiology, Center for Molecular Medicine Cologne (CMMC), 15 Cologne Excellence Cluster in Aging Associated Diseases (CECAD), 16 University of Cologne, Weyertal 119, 50931 Cologne, Germany 17 18 19 20 21 Running head: Fitting calcium dynamics: a direct method 22 23 24 25 26 Corresponding author: 27 28 Christophe Pouzat 29 Cerebral Physiology Laboratory 30 Université Paris-Descartes 31 CNRS, UMR 8118 32 45 rue des Saints-Pères 33 75006 Paris 34 France 35 Email: [email protected] 36 Tel: +33 1 42 86 38 28 37 Fax: +33 1 42 86 38 30 38 39 Articles in PresS. J Neurophysiol (December 2, 2009). doi:10.1152/jn.00414.2009
منابع مشابه
Quantitative estimation of calcium dynamics from ratiometric measurements: a direct, nonratioing method.
Measuring variations of intracellular free calcium concentration through the changes in fluorescence of a calcium-sensitive dye is a ubiquitous technique in neuroscience. Despite its popularity, confidence intervals (CIs) on the estimated parameters of calcium dynamics models are seldom given. To address this issue, we have developed a two-stage model for ratiometric measurements obtained with ...
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تاریخ انتشار 2009